MONTE CARLO SIMULATIONS OF THE DISTRIBUTIONS OF INTRA- AND EXTRA-VESICULAR IONS AND MEMBRANE ASSOCIATED CHARGES IN HYBRID LIPOSOMES COMPOSED OF NEGATIVELY CHARGED TETRAETHER AND ZWITTERIONIC DIESTER PHOSPHOLIPIDS

Monte Carlo simulations of the distributions of intra- and extra-vesicular ions and membrane associated charges in hybrid liposomes composed of negatively charged tetraether and zwitterionic diester phospholipids

Here, we model a negatively charged lipid vesicle, composed of a mixture of bipolar tetraether and diester (or diether) phospholipid molecules, by a spherical shell that has zero ion permeability.We take into consideration all the charge-charge interactions between intra-vesicular ions, extra-vesicular ions, and membrane lipid associated charges.Mo

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Effect of plasma viremia on apoptosis and immunophenotype of dendritic cells subsets in acute SIVmac239 infection of Chinese rhesus macaques.

Non-human primates such as Chinese rhesus macaques (Ch Rhs) provide good animal models for research on human infectious diseases.Similar to humans, there are two principal subsets of dendritic cells (DCs) in the peripheral blood of Ch Rhs: myeloid DCs (mDCs) and plasmacytoid DCs (pDCs).In this study, two-color fluorescence-activated cell sorting (F

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Daclatasvir: potential role in hepatitis C

Choongho Lee College of Pharmacy, Dongguk University-Seoul, Goyang, COMPLETE COLLAGEN TROPICAL BREEZE Republic of Korea  Abstract: Chronic hepatitis C virus (HCV) infection is responsible for the development of liver cirrhosis and hepatocellular carcinoma.It has been a tremendous burden on global health care systems.With the advent of a number

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Differential Expression of Serum TUG1, LINC00657, miR-9, and miR-106a in Diabetic Patients With and Without Ischemic Stroke

Background: Ischemic stroke is one of the serious complications of diabetes.Non-coding RNAs are established as promising biomarkers for diabetes and its complications.The present research Oil Squirters investigated the expression profiles of serum TUG1, LINC00657, miR-9, and miR-106a in diabetic patients with and without stroke.Methods: A total of

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