Monte Carlo simulations of the distributions of intra- and extra-vesicular ions and membrane associated charges in hybrid liposomes composed of negatively charged tetraether and zwitterionic diester phospholipids
Here, we model a negatively charged lipid vesicle, composed of a mixture of bipolar tetraether and diester (or diether) phospholipid molecules, by a spherical shell that has zero ion permeability.We take into consideration all the charge-charge interactions between intra-vesicular ions, extra-vesicular ions, and membrane lipid associated charges.Mo